Nagarajan A

Nailing down the culprit gene for beating diabetes—a case of duelling effect on rice grain protein

Leave a Comment / diabetes, health care /

Despite diabetes being an age-old disease of humanity, it still leans in healthcare management, relying on evidence-based interventions termed the lean management system rather than cure. Obesity is the risk factor for the progression of diabetes and the greater risk exerted by diabetes for cardiovascular disease due to the impact of this metabolic disease on […]

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First CRISPR’d rice with multi-pathogen resistance

Leave a Comment / genetic engineering, multi-pathogen resistance, rice /

Lesion mimic mutants (LMMs) constitutively and spontaneously display genetic lesions (necrotic spots of dead cells) in the absence of pathogenic infection, identical to disease-caused lesions due to likeness between the non-pathogenic and pathogenic syndromes associated with hypersensitive response and cell death. The broad-spectrum, nonrace-specific resistance expressed by these mutants to fungal and bacterial rice pathogens

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Catalase genes as a handle for manipulating rice blast resistance

Leave a Comment / fitness costs, immune homeostasis, tolerance /

Effectors, predominantly of proteinaceous in nature are secretions by pathogenic bacteria and, filamentous oomycete and fungi intended to neutralise the first layer of defense termed pattern-triggered immunity (PTI) also termed as basal immunity in the two-layered plant defense strategy. While in the second layer of defense, effectors are recognised by the host resistance proteins directly

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